Actually, you've done a very good job describing the largely subjective side of engine performance. IOW, I get it. The answer is probably not going to be what you want to hear. In a nutshell, it's all about the shape of the power curve and the amount of graph area below it...usable power. Horsepower and mph (along with price tags) get virtually all of the attention because...drum roll please...they're easily stated. The quantitative side always is. Most will, quite naturally, do a little mental math, something along the lines of "
X displacement will return Xmph for X dollars" and make a decision based on those criteria alone. Once in the saddle, however, the qualitative side (which I define as pretty much everything else) starts coming into view. That's where things get complicated...
The more miles you accumulate, the clearer the picture. IMHO, you're a quick study.
Until a little over 15 years ago, an honest 60mph bike was quite an achievement. 124cc tunes were the limit and very expensive, done right. Naturally, that was a driving force and, limiting speeds to ~60mph (and for short bursts at that), a lot of things sort of fell into place...including riding expectations. When the Wave 100 and Nice 110s reached the west, circa 2001, with tunes as big as ~140cc possible, a year later and 160ish displacements a year after that, the whole scene was turned upside down. Now, 80mph+ was possible for about half the cost of a high end Takegawa, or Kitaco, tune...better everything and way more power to boot (at least until the US economy was tanked and the Dollar lost half it's value against the Euro and the Yen, but that's another topic) what's not to like? The answer is "imbalance". There is nothing on a bike this size, or smaller...which includes the Z50, CT70, MSX125 (a.k.a. Grom) and the new-gen Monkey...that is truly suitable for high freeway speeds. The machines are too lightweight short wheelbased, the tire diameters take a beating at speed, due to basic laws of physics and the engines have to be taken to power levels that render than less than bulletproof. Look at the current offerings from Honda & Kawasaki; clearly, those manufacturers know what they're doing.
First off, comes the goal. Clearly defined, for a road bike, that means a realistic speed range...which, somewhat ironically, constrains peak power & displacement to sustainable (in practical terms) limits. Next up comes the rolling chassis; matching brake & suspension upgrades can easily surpass the cost of an engine, or engine mods. IMO, 60mph represents the high end of sustained cruising speed on any of these bikes. Doubtless, opinions will vary on this subject. That said, I've come to really appreciate the OEM approach to balance and practicality. It's nowhere near as easy as most believe and it surely doesn't come cheap. This is where the field gets thinned in a hurry. It takes just the right combination of dedication, expectation and budget to realize the kind of machine you want. Again, judging by your stated speed range, you're well on your way toward adjusting the balance.
FWIW, I started off the same way...big power as the top priority. My main rider was supposed to be the purple bike, which can easily
sustain 65mph. It only took a few banzai blasts to realize that 80mph is best for a few "war stories". It didn't stay boast-worthy for very long (if it ever was). Circa 2018, a 190 Daytona motor can easily be tuned to exceed that. My red bike was supposed to be the "beater". But, even after a year of riding the much faster bike exclusively, the red bike has gotten virtually all of the miles...closing in on 25K as of the 15th of this month. The reason is that it met the power goals you mentioned in the OP. (Yes, that was enough to make me focus on the rest of the bike ever since.) The fact is, nothing feels "fast" for very long...even if it is dangerously overpowered. In an extremely long-winded way, I'm saying that it's not about the destination...it's about the journey and everything required to make that as enjoyable as possible. That, IMHO, is where drive and sustainability are to be found.
To answer your engine tuning questions directly, in context, you are looking to trade peak horsepower for a flatter torque curve...with the tradeoff being a big gain in under-the-curve (a.k.a. average/usable) power. Honda began doing this in the late `90s. First, they went to an under-square which typically results in a flat torque curve. Then, they really put a proverbial thumb-on-the-scale, going to a desaxe configuration. The Nice motor is a stomper, not a screamer; the power curve is (by traditional old-school standards) kinda weird...torque peak around 5K, hp peak at 8K, and all done by the time the tach shows low 9K rpm. On the SOTP dyno, it's an engine that pulls like freight train from just above idle into the mid-50s, then suddenly just runs out of breath, with no discernible power peak. The new 125 motor, as used in the MSX125/Grom, is just a slightly enlarged version of that configuration...~2mm on both bore & stroke...making virtually the same peak power but at slightly lower revs. That's why first gear felt "anemic" (it isn't really) but it pulled nicely to redline in top gear.
It may be possible to shift the power curve with a milder (less hp-biased) cam and re-gear the bike to match. Best advice I can offer...and it may come across as harsh...is to go for a 54mm crank. Nothing will give you the kind of torque increase of a longer stroke. That still comes up a little short of the 55.5mm arm of the Nice as well as the 57mm MSX crank. If you can accept boring your cases to accept a 54mm bore, the extra ~15cc should compensate for at least some of the torque curve difference(s). You'll be able to really "see" the difference once you've dialed-in the new, matching, sprocket combo. The other parameter...stay off the freeway, it's no place for anything under ~250cc & ~500lbs (combined bike + rider) mass, with ~17" wheels; those are minimums.