The biggest power gains will come from port work. It is possible to fit larger valves, but this is a can of worms as there are variations in head design over the years. A competent performance engine builder should be able to figure it out for you, though the costs may add-up. As I recall, the largest intake valves Honda ever used with the 72cc engine was 23mm. It may be possible to go as large as 25mm, depending upon the specific head on your motor.
Even with the stock size intake valve, opening up the ports can really wake up the motor. You want to begin by removing all casting flash, then open the short-side raidus of the port just beneath the valve, then enlarging the manifold end and blending the two ends together in a smooth transition. In effect "straightening out" the port. This can be done on the exhaust side as well. The intake port should be left with a relatively rough finish for fuel atomization; the exhaust port can be polished smooth. Do not grind away the exposed portions of the valve guides.
Once the ports have been improved, you'll need a hairier cam to take advantage of the increased breathing capability. 72cc is still small displacement, so you'll need to rev the motor fairly high to make power. Cap it off with an 18mm carb, K&N filter and a decent exhaust and you should see 50mph on the flat.
Adding spark advance, either the old mechanical type as used with the "H" motors or CDI type will make the engine rev better and have crisper throttle response. Increasing compression will also help, especially with top end hp. Again, you have to do your homework to get the correct hi-comp piston.
Adding an 85/88cc kit is almost a no-brainer as the cost is nearly the same as boring/honing & a new piston assembly for your existing cylinder. Plus it's another 5mph+.
Forget the forced induction and nitrous. The setups are complicated, fiendishly tricky to setup and expensive. I've yet to actually see a supercharger or turbo that actually worked properly on one of these bikes. Nitrous is good for about 2-4hp, if you really know what you're doing. Expect a toasted piston, or three, along the way. Go too far and expect the engine to go "bang" in a big way